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American Melody, Lower Mississippi River Cruise ex Memphis to New Orleans
River Cruise
Cruise Departs: 16 May 2025
Cruise Ship: American Melody

7 Night Cruise sailing from Memphis to New Orleans onboard American Melody. Hotel stay pre-cruise in Memphis.

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American Melody, Complete Mississippi River Cruise ex New Orleans to St. Paul
River Cruise
Cruise Departs: 23 May 2025
Cruise Ship: American Melody

21 Night Cruise sailing from New Orleans to St Paul onboard American Melody. Complimentary hotel stay pre-cruise in New Orleans.

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American Melody, Upper Mississippi River Cruise ex St. Paul to Alton
River Cruise
Cruise Departs: 13 June 2025
Cruise Ship: American Melody

7 Night Cruise sailing from Red Wing to Alton onboard American Melody. Complimentary hotel stay pre-cruise in St Paul.

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American Melody, Grand Ohio River Cruise ex St. Louis to Pittsburgh
River Cruise
Cruise Departs: 20 June 2025
Cruise Ship: American Melody

14 Night Cruise sailing from St Louis to Pittsburgh onboard American Melody. Complimentary hotel stay pre-cruise in St Louis.

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American Melody, Grand Ohio River Cruise ex Pittsburgh to St Louis
River Cruise
Cruise Departs: 4 July 2025
Cruise Ship: American Melody

14 Night Cruise sailing from Pittsburgh to St Louis onboard American Melody. Complimentary hotel stay pre-cruise in Pittsburgh.

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American Melody, Upper Mississippi River Cruise ex St. Louis to Red Wing
River Cruise
Cruise Departs: 18 July 2025
Cruise Ship: American Melody

7 Night Cruise sailing from Alton to Red Wing onboard American Melody. Complimentary hotel stay pre-cruise in St Louis.

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American Melody, Upper Mississippi River Cruise ex St. Paul to Alton
River Cruise
Cruise Departs: 25 July 2025
Cruise Ship: American Melody

7 Night Cruise sailing from Red Wing to Alton onboard American Melody. Complimentary hotel stay pre-cruise in St Paul.

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American Melody, Grand Ohio River Cruise ex St. Louis to Pittsburgh
River Cruise
Cruise Departs: 1 August 2025
Cruise Ship: American Melody

14 Night Cruise sailing from St Louis to Pittsburgh onboard American Melody. Complimentary hotel stay pre-cruise in St Louis.

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American Melody, Grand Ohio River Cruise ex Pittsburgh to St Louis
River Cruise
Cruise Departs: 15 August 2025
Cruise Ship: American Melody

14 Night Cruise sailing from Pittsburgh to St Louis onboard American Melody. Complimentary hotel stay pre-cruise in Pittsburgh.

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American Melody, Upper Mississippi River Cruise ex St. Louis to Red Wing
River Cruise
Cruise Departs: 29 August 2025
Cruise Ship: American Melody

7 Night Cruise sailing from Alton to Red Wing onboard American Melody. Complimentary hotel stay pre-cruise in St Louis.

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American Melody, Upper Mississippi River Cruise ex St. Paul to Alton
River Cruise
Cruise Departs: 5 September 2025
Cruise Ship: American Melody

7 Night Cruise sailing from Red Wing to Alton onboard American Melody. Complimentary hotel stay pre-cruise in St Paul.

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American Melody, Upper Mississippi River Cruise ex St. Louis to Red Wing
River Cruise
Cruise Departs: 12 September 2025
Cruise Ship: American Melody

7 Night Cruise sailing from Alton to Red Wing onboard American Melody. Complimentary hotel stay pre-cruise in St Louis.

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American Melody, Upper Mississippi River Cruise ex St. Paul to Alton
River Cruise
Cruise Departs: 19 September 2025
Cruise Ship: American Melody

7 Night Cruise sailing from Red Wing to Alton onboard American Melody. Complimentary hotel stay pre-cruise in St Paul.

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American Melody, Upper Mississippi River Cruise ex St. Louis to Red Wing
River Cruise
Cruise Departs: 26 September 2025
Cruise Ship: American Melody

7 Night Cruise sailing from Alton to Red Wing onboard American Melody. Complimentary hotel stay pre-cruise in St Louis.

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American Melody, Upper Mississippi River Cruise ex St. Paul to Alton
River Cruise
Cruise Departs: 3 October 2025
Cruise Ship: American Melody

7 Night Cruise sailing from Red Wing to Alton onboard American Melody. Complimentary hotel stay pre-cruise in St Paul.

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American Melody, Upper Mississippi River Cruise ex St. Louis to Red Wing
River Cruise
Cruise Departs: 10 October 2025
Cruise Ship: American Melody

7 Night Cruise sailing from Alton to Red Wing onboard American Melody. Complimentary hotel stay pre-cruise in St Louis.

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American Melody, Grand Heartland Cruise ex St Paul to New Orleans
River Cruise
Cruise Departs: 17 October 2025
Cruise Ship: American Melody

14 Night Cruise sailing from Red Wing to New Orleans onboard American Melody. Complimentary hotel stay pre-cruise in St Paul.

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Lower Mississippi River Cruise - American Cruise Lines
Cruise and Stay
Cruise Departs: 31 October 2025
Cruise Ship: American Melody

Cruise & Stay 8 nights from New Orleans to Memphis aboard the brand new American Riverboat - American Melody.

From: US $5,275
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Lower Mississippi River Cruise - American Cruise Lines
Cruise and Stay
Cruise Departs: 7 November 2025
Cruise Ship: American Melody

Cruise & Stay 8 nights from Memphis to New Orleans aboard the American Riverboat - American Melody.

From: US $5,275
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American Melody, Historic Mississippi River ex New Orleans Return
River Cruise
Cruise Departs: 14 November 2025
Cruise Ship: American Melody

7 Night Cruise & Stay sailing from New Orleans, Louisiana, USA onboard American Melody.

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