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American Serenade, Lower Mississippi River Cruise ex New Orleans to Memphis
River Cruise
Cruise Departs: 16 May 2025
Cruise Ship: American Serenade

7 Night Cruise sailing from New Orleans to Memphis onboard American Serenade. Hotel stay pre-cruise in New Orleans.

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American Serenade, Lower Mississippi River Cruise ex Memphis to New Orleans
River Cruise
Cruise Departs: 23 May 2025
Cruise Ship: American Serenade

7 Night Cruise sailing from Memphis to New Orleans onboard American Serenade. Hotel stay pre-cruise in Memphis.

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American Serenade, Lower Mississippi River Cruise ex New Orleans to Memphis
River Cruise
Cruise Departs: 30 May 2025
Cruise Ship: American Serenade

7 Night Cruise sailing from New Orleans to Memphis onboard American Serenade. Hotel stay pre-cruise in New Orleans.

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American Serenade, Lower Mississippi River Cruise ex Memphis to New Orleans
River Cruise
Cruise Departs: 6 June 2025
Cruise Ship: American Serenade

7 Night Cruise sailing from Memphis to New Orleans onboard American Serenade. Hotel stay pre-cruise in Memphis.

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American Serenade, Complete Mississippi River Cruise ex New Orleans to St. Paul
River Cruise
Cruise Departs: 13 June 2025
Cruise Ship: American Serenade

21 Night Cruise sailing from New Orleans to St Paul onboard American Serenade. Complimentary hotel stay pre-cruise in New Orleans.

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American Serenade, Upper Mississippi River Cruise ex St. Paul to Alton
River Cruise
Cruise Departs: 4 July 2025
Cruise Ship: American Serenade

7 Night Cruise sailing from Red Wing to Alton onboard American Serenade. Complimentary hotel stay pre-cruise in St Paul.

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American Serenade, Upper Mississippi River Cruise ex St. Louis to Red Wing
River Cruise
Cruise Departs: 11 July 2025
Cruise Ship: American Serenade

7 Night Cruise sailing from Alton to Red Wing onboard American Serenade. Complimentary hotel stay pre-cruise in St Louis.

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American Serenade, Upper Mississippi River Cruise ex St. Paul to Alton
River Cruise
Cruise Departs: 18 July 2025
Cruise Ship: American Serenade

7 Night Cruise sailing from Red Wing to Alton onboard American Serenade. Complimentary hotel stay pre-cruise in St Paul.

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American Serenade, Upper Mississippi River Cruise ex St. Louis to Red Wing
River Cruise
Cruise Departs: 25 July 2025
Cruise Ship: American Serenade

7 Night Cruise sailing from Alton to Red Wing onboard American Serenade. Complimentary hotel stay pre-cruise in St Louis.

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American Serenade, Upper Mississippi River Cruise ex St. Paul to Alton
River Cruise
Cruise Departs: 1 August 2025
Cruise Ship: American Serenade

7 Night Cruise sailing from Red Wing to Alton onboard American Serenade. Complimentary hotel stay pre-cruise in St Paul.

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American Serenade, Upper Mississippi River Cruise ex St. Louis to Red Wing
River Cruise
Cruise Departs: 8 August 2025
Cruise Ship: American Serenade

7 Night Cruise sailing from Alton to Red Wing onboard American Serenade. Complimentary hotel stay pre-cruise in St Louis.

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American Serenade, Grand Heartland Cruise ex St Paul to New Orleans
River Cruise
Cruise Departs: 15 August 2025
Cruise Ship: American Serenade

14 Night Cruise sailing from Red Wing to New Orleans onboard American Serenade. Complimentary hotel stay pre-cruise in St Paul.

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American Serenade, Lower Mississippi River Cruise ex New Orleans to Memphis
River Cruise
Cruise Departs: 16 October 2025
Cruise Ship: American Serenade

7 Night Cruise sailing from New Orleans to Memphis onboard American Serenade. Hotel stay pre-cruise in New Orleans.

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American Serenade, Lower Mississippi River Cruise ex Memphis to New Orleans
River Cruise
Cruise Departs: 23 October 2025
Cruise Ship: American Serenade

7 Night Cruise sailing from Memphis to New Orleans onboard American Serenade. Hotel stay pre-cruise in Memphis.

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American Serenade, 7 Night Historic Mississippi River ex New Orleans Return
River Cruise
Cruise Departs: 7 November 2025
Cruise Ship: American Serenade

7 Night Cruise & Stay sailing from New Orleans, Louisiana, USA onboard American Serenade.

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Lower Mississippi River Cruise - American Cruise Lines
Cruise and Stay
Cruise Departs: 9 November 2025
Cruise Ship: American Serenade

Cruise & Stay 8 nights from Memphis to New Orleans aboard the American Riverboat - American Serenade.

From: US $5,275
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American Serenade, 7 Night Historic Mississippi River ex New Orleans Return
River Cruise
Cruise Departs: 13 November 2025
Cruise Ship: American Serenade

7 Night Cruise & Stay sailing from New Orleans, Louisiana, USA onboard American Serenade.

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American Serenade, 7 Night Historic Mississippi River ex New Orleans Return
River Cruise
Cruise Departs: 19 November 2025
Cruise Ship: American Serenade

7 Night Cruise & Stay sailing from New Orleans, Louisiana, USA onboard American Serenade.

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American Serenade, 7 Night Historic Mississippi River ex New Orleans Return
River Cruise
Cruise Departs: 25 November 2025
Cruise Ship: American Serenade

7 Night Cruise & Stay sailing from New Orleans, Louisiana, USA onboard American Serenade.

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American Serenade, 7 Night Historic Mississippi River ex New Orleans Return
River Cruise
Cruise Departs: 1 December 2025
Cruise Ship: American Serenade

7 Night Cruise & Stay sailing from New Orleans, Louisiana, USA onboard American Serenade.

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