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Lower Mississippi River Cruise - American Cruise Lines
Cruise and Stay
Cruise Departs: 13 April 2027
Cruise Ship: American Splendor

Cruise & Stay 8 nights from Memphis to New Orleans aboard a classic paddlewheeler - American Splendor.

From: US $4,925
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Choose Your Amenity - Air Credit or Hotel Package or Enhanced WiFi
Cruise Only
Cruise Departs: 15 April 2027
Cruise Ship: World Traveller

8 night expedition cruise aboard the intimate yacht, World Traveller.

From: US $5,443
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Choose Your Amenity - Air Credit or Hotel Package or Enhanced WiFi
Cruise Only
Cruise Departs: 16 April 2027
Cruise Ship: World Voyager

9 night expedition cruise aboard the intimate yacht, World Voyager.

From: US $5,988
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Lower Mississippi River Cruise - American Cruise Lines
Cruise and Stay
Cruise Departs: 16 April 2027
Cruise Ship: American Melody

Cruise & Stay 8 nights from Memphis to New Orleans aboard the American Riverboat - American Melody.

From: US $5,995
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Lower Mississippi River Cruise - American Cruise Lines
Cruise and Stay
Cruise Departs: 16 April 2027
Cruise Ship: American Serenade

Cruise & Stay 8 nights from New Orleans to Memphis aboard the American Riverboat - American Serenade.

From: US $5,995
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Choose Your Amenity - Air Credit or Hotel Package or Enhanced WiFi
Cruise Only
Cruise Departs: 17 April 2027
Cruise Ship: World Navigator

10 night expedition cruise aboard the intimate yacht, World Navigator.

From: US $6,714
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Lower Mississippi River Cruise - American Cruise Lines
Cruise and Stay
Cruise Departs: 20 April 2027
Cruise Ship: American Splendor

Cruise & Stay 8 nights from New Orleans to Memphis aboard the American Paddlesteamer - American Splendor.

From: US $4,925
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Choose Your Amenity - Air Credit or Hotel Package or Enhanced WiFi
Cruise Only
Cruise Departs: 23 April 2027
Cruise Ship: World Traveller

8 night expedition cruise aboard the intimate yacht, World Traveller.

From: US $5,443
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Lower Mississippi River Cruise - American Cruise Lines
Cruise and Stay
Cruise Departs: 23 April 2027
Cruise Ship: American Serenade

Cruise & Stay 8 nights from Memphis to New Orleans aboard the American Riverboat - American Serenade.

From: US $5,995
View Deal
Lower Mississippi River Cruise - American Cruise Lines
Cruise and Stay
Cruise Departs: 23 April 2027
Cruise Ship: American Melody

Cruise & Stay 8 nights from New Orleans to Memphis aboard the brand new American Riverboat - American Melody.

From: US $5,995
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Choose Your Amenity - Air Credit or Hotel Package or Enhanced WiFi
Cruise Only
Cruise Departs: 27 April 2027
Cruise Ship: World Navigator

10 night expedition cruise aboard the intimate yacht, World Navigator.

From: US $6,714
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Lower Mississippi River Cruise - American Cruise Lines
Cruise and Stay
Cruise Departs: 27 April 2027
Cruise Ship: American Splendor

Cruise & Stay 8 nights from Memphis to New Orleans aboard a classic paddlewheeler - American Splendor.

From: US $4,925
View Deal
Lower Mississippi River Cruise - American Cruise Lines
Cruise and Stay
Cruise Departs: 30 April 2027
Cruise Ship: American Melody

Cruise & Stay 8 nights from Memphis to New Orleans aboard the American Riverboat - American Melody.

From: US $5,995
View Deal
Lower Mississippi River Cruise - American Cruise Lines
Cruise and Stay
Cruise Departs: 30 April 2027
Cruise Ship: American Serenade

Cruise & Stay 8 nights from New Orleans to Memphis aboard the American Riverboat - American Serenade.

From: US $5,995
View Deal
BONUS USD200 PP Onboard Credit + Free Bottle of Champagne!
Cruise Only
Cruise Departs: 1 May 2027
Cruise Ship: World Traveller

8 night expedition cruise aboard the intimate yacht, World Traveller.

From: US $4,718
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Lower Mississippi River Cruise - American Cruise Lines
Cruise and Stay
Cruise Departs: 4 May 2027
Cruise Ship: American Splendor

Cruise & Stay 8 nights from New Orleans to Memphis aboard the American Paddlesteamer - American Splendor.

From: US $4,925
View Deal
Choose Your Amenity - Air Credit or Hotel Package or Enhanced WiFi
Cruise Only
Cruise Departs: 7 May 2027
Cruise Ship: World Navigator

7 night expedition cruise aboard the intimate yacht, World Navigator.

From: US $5,437
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Lower Mississippi River Cruise - American Cruise Lines
Cruise and Stay
Cruise Departs: 7 May 2027
Cruise Ship: American Serenade

Cruise & Stay 8 nights from Memphis to New Orleans aboard the American Riverboat - American Serenade.

From: US $5,995
View Deal
Lower Mississippi River Cruise - American Cruise Lines
Cruise and Stay
Cruise Departs: 7 May 2027
Cruise Ship: American Melody

Cruise & Stay 8 nights from New Orleans to Memphis aboard the brand new American Riverboat - American Melody.

From: US $5,995
View Deal
BONUS USD200 PP Onboard Credit + Free Bottle of Champagne!
Cruise Only
Cruise Departs: 11 May 2027
Cruise Ship: World Voyager

9 night expedition cruise aboard the intimate yacht, World Voyager.

From: US $5,239
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